Optimizing DC cross-presentation
Orchestrating the immune response
Flinsenberg, Thijs
- Promoter:
- Prof.dr. E.E.S. (Edward) Nieuwenhuis
- Co-promoter:
- Dr. M.L. (Marianne) Boes & dr. J.J. (Jaap Jan) Boelens
- Research group:
- Boes
- Date:
- October 3, 2014
- Time:
- 14:30 h
Summary
This thesis describes new insights in dendritic cell biology and contains disquisitions on antigen processing and presentation as well as the manipulation of these mechanisms using receptor mediated uptake. The work is aimed at better understanding dendritic cell (DC) biology, thereby contributing to pre-clinical work on DC vaccinations, which are being developed by the Utrecht Dendritic cells Against CancEr (U-DANCE) group.